How Does the Benzamide Antipsychotic Amisulpride get into the Brain?—An In Vitro Approach Comparing Amisulpride with Clozapine
نویسندگان
چکیده
منابع مشابه
Clozapine augmentation with amisulpride.
A 42-year-old man with treatmentresistant schizophrenia presented a progressive clinical worsening under clozapine treatment (450 mg/d). He experienced worsening auditory hallucinations, increased distress and decreased working and social functioning (Positive and Negative Syndrome Scale [PANSS] score 97; positive subscale 21; negative subscale 31; general subscale 45). He experienced several s...
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Psychopharmaca are used in treatment of psychiatric illnesses and disorders, among other therapeutic possibilities. The choice of the psychopharmaca is determined by the specific psychopathology of the patient, within the diagnostic categories, according to the current classification of diseases and disorders. With the advances in pharmaco industry, the range of drugs used in the everyday clini...
متن کاملAmisulpride has no effect on plasma clozapine concentrations.
To the Editors: To date, only a few systematic studies analyzing the use of combinations of antipsychotics have been undertaken. However, knowing how clozapine and amisulpride interact could be particularly important as patients with schizophrenia might well profit from such a combination treatment; indeed, a few case reports and studies support this notion. Good efficacy and tolerability of th...
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Background: Therapeutic options for patients with treatment-resistant schizophrenia are limited. In such cases, a combination of atypical antipsychotic drugs is an often used strategy. We tested the hypothesis that the combination of amisulpride and clozapine would lead to long-term improvement in this patient group. Objective: 15 patients with treatment-resistant schizophrenia participated in ...
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BACKGROUND Burning mouth syndrome (BMS) is a frequently occurring disease characterized by a burning or painful sensation in the tongue and/or other oral sites without clinical mucosal abnormalities or lesions. Its etiopathology is unknown, although local, systemic, and psychological factors have been associated with BMS. The syndrome is multifactorial, and its management remains unsatisfactory...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2003
ISSN: 0893-133X,1740-634X
DOI: 10.1038/sj.npp.1300244